A pharmacist may call a prescriber and receive verbal permission to change all of the following on a Schedule II prescription EXCEPT:

When discussing changes to a Schedule II prescription, it is important to understand the regulatory framework that governs these substances. A pharmacist cannot change the drug name on a prescription for a controlled substance, particularly a Schedule II drug, without obtaining a new prescription from the prescriber. This is due to the critical importance of the specific medication prescribed, as the effects, potential for misuse, and patient safety considerations are closely tied to the exact drug being dispensed.

On the other hand, certain modifications can be made with the prescriber's verbal permission. For example, changes to the dosage strength, quantity prescribed, and directions for use can all be made after confirming with the prescriber. These adjustments fall under the pharmacist's professional responsibilities and clinical judgment, provided that they are consistent with the therapeutic needs of the patient and are properly documented.

In summary, the inability to change the drug name serves to protect patient safety and ensure that the medication being dispensed is exactly what the prescriber intended, which is why it cannot be altered even with verbal permission.