Where can a pharmacist find information to determine if generic warfarin tablets are bioequivalent to brand name Coumadin tablets?

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The Orange Book, known officially as the "Approved Drug Products with Therapeutic Equivalence Evaluations," is the primary resource for determining whether generic medications are bioequivalent to their brand-name counterparts. It provides information on drug formulations and whether generic versions have been found to be therapeutically equivalent to the innovator brand. Specifically, it lists products that have been evaluated for bioequivalence, which is essential for pharmacists to confirm the interchangeability of generic warfarin with Coumadin.

The other resources mentioned serve different purposes. The Yellow Book is focused on health information for travelers, the Green Book pertains to veterinary drugs, and the Red Book generally contains pricing information and availability of drugs but does not specifically address bioequivalence. Thus, the Orange Book is the correct reference for pharmacists needing to verify the bioequivalence status between warfarin tablets and Coumadin.

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