Which of the following provides information about the risks relative to benefits of a drug?

The correct answer is C, a Medication Guide. A Medication Guide is a specific type of patient information that is required by the FDA for certain medications that have the potential for serious adverse effects or that are associated with particular risks and benefits. These guides are designed to help patients understand the risks associated with a medication, what to watch for, how to take the medication safely, and the expected benefits. They provide a clear, concise format that communicates important safety information directly to patients.

In contrast, a contraindication list indicates situations or conditions in which a drug should not be used, which does not inherently explain the balance of risks and benefits. A black box warning, while also related to safety, is typically focused on the most serious risks associated with a drug rather than a comprehensive overview of both risks and benefits. A summary of clinical trial results may provide data on efficacy and safety, but it often lacks the straightforward patient-focused guidance that a Medication Guide offers regarding the comparative risks and benefits. This makes the Medication Guide the most appropriate choice for understanding the risks relative to benefits of a drug.